Depressive Symptoms Are Associated With Objectively Measured Sleep Parameters in Kidney Transplant Recipients

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Sleep apnea is not associated with worse outcomes in kidney transplant recipients

Obstructive sleep apnea(OSA) is one of the most common sleep disorders in kidney transplant recipients, however its long-term consequences have only rarely been investigated. Here, we hypothesized that the presence of OSA would be associated with higher risk of mortality and faster decline of graft function in kidney transplant recipients. In a prospective cohort study 100 prevalent kidney tran...

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Expression Levels of Obesity-Related Genes Are Associated with Weight Change in Kidney Transplant Recipients

BACKGROUND The aim of this study was to investigate the association of gene expression profiles in subcutaneous adipose tissue with weight change in kidney transplant recipients and to gain insights into the underlying mechanisms of weight gain. METHODOLOGY/PRINCIPAL FINDINGS A secondary data analysis was done on a subgroup (n = 26) of existing clinical and gene expression data from a larger ...

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Genetic polymorphisms of Interleukin-18 are not associated with allograft function in kidney transplant recipients

Interleukin 18 (IL-18) is a proinflammatory cytokine that plays a role in host defense by upregulating both innate and acquired immune responses. Analysis of IL18 polymorphisms may be clinically important since their roles have been recognized in a variety of inflammatory and autoimmune disorders. However, the role of this cytokine polymorphisms in kidney transplant still remains unclear. In th...

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Types of coping strategies are associated with increased depressive symptoms in patients with obstructive sleep apnea.

STUDY OBJECTIVES Some, but not all, researchers report that obstructive sleep apnea (OSA) patients experience increased depressive symptoms. Many psychological symptoms of OSA are explained in part by other OSA comorbidities (age, hypertension, body mass). People who use more passive and less active coping report more depressive symptoms. We examined relationships between coping and depressive ...

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ژورنال

عنوان ژورنال: Journal of Clinical Sleep Medicine

سال: 2017

ISSN: 1550-9389,1550-9397

DOI: 10.5664/jcsm.6542